Comparative evaluation of 7 helminth antigens in the enzyme-linked immunosorbent assay (E.L.I.S.A.)
| Autor: | N. Weiss, F. Speiser |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Helminthiasis
Enzyme-Linked Immunosorbent Assay Biology Microbiology Cellular and Molecular Neuroscience Epitopes Antigen Species Specificity Helminths parasitic diseases medicine Fasciola hepatica Animals Antigens Molecular Biology Ascaris suum Pharmacology Cell Biology biology.organism_classification medicine.disease Canis Immunology Molecular Medicine Schistosoma mansoni Toxocara canis |
| Zdroj: | Experientia. 35(11) |
| ISSN: | 0014-4754 |
| Popis: | 112 sera from Europeans with parasitologically proven helminthiasis were tested in the enzyme-linked immunosorbent assay (E.L.I.S.A.) against 6 crude extracts of various helminths (2 of adult worms: Dipetalonema viteae, Fasciola hepatica; 3 of eggs: Ascaris suum, Toxocara canis, Schistosoma mansoni; and of Echinococcus granulosus scolices) and against bovine hydatid fluid. Each serum was tested simultaneously at a fixed dilution of 1:160 against all antigens. Extensive cross-reactions were observed, leading to the conclusion that non-purified helminth antigens, even in combination, are of limited value for reliable serodiagnosis in E.L.I.S.A. |
| Databáze: | OpenAIRE |
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