Amygdala central nucleus modulation of cerebellar learning in female rats
| Autor: | Samantha R. Pierson, Sean J. Farley, John H. Freeman |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty 2019-20 coronavirus outbreak Cerebellum Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Amygdala Article Behavioral Neuroscience chemistry.chemical_compound Internal medicine Male rats Animals Medicine Rats Long-Evans Muscimol business.industry Central Amygdaloid Nucleus Conditioning Eyelid Rats respiratory tract diseases Animal learning medicine.anatomical_structure Endocrinology nervous system chemistry Amygdala Central Nucleus Female Rabbits business |
| Zdroj: | Behav Neurosci |
| ISSN: | 1939-0084 0735-7044 |
| DOI: | 10.1037/bne0000441 |
| Popis: | Previous studies found that inactivation of the central amygdala (CeA) severely impaired acquisition of cerebellum-dependent delay eye-blink conditioning (EBC) in male rats and rabbits. Sex differences in EBC and the effects of stress on EBC have been reported and might be related to sex differences in amygdala modulation of cerebellar learning. The current study examined the effects of CeA inactivation with muscimol on acquisition and retention of EBC in female rats. Like male rats, CeA inactivation in female rats severely impaired EBC acquisition and retention. Comparison of the female data with previously published data from males indicates no substantive sex differences in the effects of CeA inactivation on acquisition or retention of EBC. The results indicate that amygdala modulation of cerebellar learning is not sex-specific. (PsycInfo Database Record (c) 2021 APA, all rights reserved). |
| Databáze: | OpenAIRE |
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