Macular and peripapillary retinal nerve fibre layer thickness in adults with amblyopia
| Autor: | Alexandra Voll, Randy A. Walker, Shehla Rubab, Paul H. Murphy, Vasudha Erraguntla |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Retinal Ganglion Cells medicine.medical_specialty Intraocular pressure Visual acuity genetic structures Optic Disk Visual Acuity Statistical difference Nerve fiber layer Nerve fibre layer Amblyopia chemistry.chemical_compound Nerve Fibers Optical coherence tomography Ophthalmology medicine Humans Macula Lutea Aged Aged 80 and over medicine.diagnostic_test business.industry Retinal General Medicine Middle Aged eye diseases Cross-Sectional Studies medicine.anatomical_structure chemistry Eye examination sense organs medicine.symptom business Tomography Optical Coherence |
| Zdroj: | Canadian Journal of Ophthalmology. 46:425-427 |
| ISSN: | 0008-4182 |
| DOI: | 10.1016/j.jcjo.2011.07.013 |
| Popis: | Objective To evaluate macular and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopic eyes compared to the fellow eye. Design Cross-sectional study. Participants 30 patients (60 eyes) older than 18 years of age with amblyopia. Methods Inclusion criteria included individuals older than 18 years, amblyopia, and best-corrected visual acuity (BCVA) ≤20/40. A complete medical history was taken and an eye examination carried out. Optical coherence tomography (OCT) was carried out on both eyes of all patients. Exclusion criteria included intraocular pressure (IOP) >23 mm Hg and eye pathology that may affect OCT measurements. The primary outcome measures were foveal thickness and average peripapillary RNFL thickness, which were compared using a paired t test. Quadrants in peripapillary scans and concentric rings in macular scans were analyzed. Results The average age was 56 years (range = 33–82 years). Visual acuity ranged from 20/40 to 20/4000 (mean = 20/275). The average peripapillary RNFL thickness was 90.6 μm (SD = 9.6 μm) in the amblyopic eye and 90.1 μm (SD = 12.1 μm) in the fellow eye ( p = 0.64). The average macular thickness in amblyopic eyes was 260.1 μm (SD = 32.0 μm), and 254.7 μm (SD = 32.5 μm) in fellow eyes ( p = 0.10). No statistical difference existed between peripapillary quadrants or macular concentric rings. These differences were smaller when the strabismic amblyopes were isolated. Conclusions There does not seem to be a difference in peripapillary RNFL or macular thickness between the amblyopic eye and fellow eye. |
| Databáze: | OpenAIRE |
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