Cupration of C2F5H: Isolation, Structure, and Synthetic Applications of [K(DMF)2][(t-BuO)Cu(C2F5)]. Highly Efficient Pentafluoroethylation of Unactivated Aryl Bromides

Autor:	Anton Lishchynskyi, Vladimir V. Grushin
Rok vydání:	2013
Předmět:	Fluorocarbons Molecular Structure Aryl General Chemistry Biochemistry Medicinal chemistry Catalysis Hydrocarbons Brominated chemistry.chemical_compound Colloid and Surface Chemistry chemistry Pentafluoroethane Reagent Yield (chemistry) Organometallic Compounds Organic chemistry Copper
Zdroj:	Journal of the American Chemical Society. 135:12584-12587
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja407017j
Popis:	Pentafluoroethane, C2F5H (HFC-125), is smoothly cuprated with preisolated or in situ-generated [K(DMF)][(t-BuO)2Cu] to give [K(DMF)2][(t-BuO)Cu(C2F5)] (1) in nearly quantitative yield. Complex 1 has been isolated, structurally characterized, and demonstrated to be an exceedingly versatile pentafluoroethylating reagent for a variety of substrates, including unactivated aryl bromides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07e3ee787ee8e621d1ad0e5e50f6656 https://doi.org/10.1021/ja407017j Zobrazit plný text záznamu