Clinical Application of the Fluid Challenge Approach in Goal-Directed Fluid Therapy: What Can We Learn From Human Studies?
| Autor: | Francisco J. Teixeira-Neto, Alexander Valverde |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cardiac output
medicine.medical_specialty Veterinary medicine Fluid responsiveness goal-directed fluid therapy Review shock 03 medical and health sciences 0302 clinical medicine Fluid therapy 030202 anesthesiology Internal medicine SF600-1100 medicine fluid responsiveness General Veterinary business.industry cardiac output 030208 emergency & critical care medicine Stroke volume fluid challenge Preload Shock (circulatory) Cardiology Veterinary Science medicine.symptom business Fluid challenge Venous return curve |
| Zdroj: | Frontiers in Veterinary Science Frontiers in Veterinary Science, Vol 8 (2021) |
| ISSN: | 2297-1769 |
| DOI: | 10.3389/fvets.2021.701377 |
| Popis: | Resuscitative fluid therapy aims to increase stroke volume (SV) and cardiac output (CO) and restore/improve tissue oxygen delivery in patients with circulatory failure. In individualized goal-directed fluid therapy (GDFT), fluids are titrated based on the assessment of responsiveness status (i.e., the ability of an individual to increase SV and CO in response to volume expansion). Fluid administration may increase venous return, SV and CO, but these effects may not be predictable in the clinical setting. The fluid challenge (FC) approach, which consists on the intravenous administration of small aliquots of fluids, over a relatively short period of time, to test if a patient has a preload reserve (i.e., the relative position on the Frank-Starling curve), has been used to guide fluid administration in critically ill humans. In responders to volume expansion (defined as individuals where SV or CO increases ≥10–15% from pre FC values), FC administration is repeated until the individual no longer presents a preload reserve (i.e., until increases in SV or CO are |
| Databáze: | OpenAIRE |
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