Giant liver hemangioma in three sisters

Autor:	J J M Van Meyel, G C Admiraal, A Van Schie, W L E Vasmel
Rok vydání:	2004
Předmět:	Ultrasound study Pathology medicine.medical_specialty Hepatology business.industry Vascular disease Liver Neoplasms education Gastroenterology Disease Middle Aged medicine.disease Hemangioma Angiopoietin Pathogenesis Liver Hemangioma Humans Medicine Female cardiovascular diseases business
Zdroj:	Journal of Gastroenterology and Hepatology. 19:344-345
ISSN:	1440-1746 0815-9319
DOI:	10.1111/j.1440-1746.2004.02890.x
Popis:	We describe a patient, in whom giant liver hemangioma (GLH) was found by ultrasound study in screening for hypertension. Two of her sisters also had GLH. One of them had become symptomatic and the hemangioma was successfully removed. The other sisters were carefully watched. Our patient didn't need any intervention in 4 years of follow-up. The pathogenesis of GLH is still unknown. Recent investigations show a role of the TIE receptor/angiopoietin system in vascular malformations. In literature we only found two other reports about a familial occurrence of liver hemangiomas. A genetic defect in familial GLH has not yet been identified.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df56c132486570525d72ae7076e52ac9 https://doi.org/10.1111/j.1440-1746.2004.02890.x Zobrazit plný text záznamu Plný text