Metastatic prostatic adenocarcinoma diagnosed in a bronchoalveolar lavage specimen: An unusual presentation of a common tumor
| Autor: | Adrienne Moul, Parvin Ganjei-Azar, Christina Kovacs, Claudia P. Rojas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Histology Immunocytochemistry Case Report Pathology and Forensic Medicine Bronchoscopy Antigen Prostate medicine prostatic adenocarcinoma lcsh:QH573-671 Metastatic Prostatic Adenocarcinoma medicine.diagnostic_test business.industry lcsh:Cytology Bronchoalveolar lavage (BAL) medicine.disease Peribronchial Thickening medicine.anatomical_structure Bronchoalveolar lavage prostate-specific antigen (PSA) Adenocarcinoma medicine.symptom business |
| Zdroj: | Journal of Cytology, Vol 33, Iss 1, Pp 43-45 (2016) Journal of Cytology / Indian Academy of Cytologists |
| ISSN: | 0970-9371 |
| Popis: | Metastatic prostatic adenocarcinoma presenting as a primary lung disease is rare. We present a 52-year-old male with a 3-month history of cough, shortness of breath, and weight loss with clinical and radiological findings suggestive of a primary lung disease: Bilateral interstitial and alveolar opacities with blunting of the costophrenic angles, multiple diffuse foci of consolidations and nodules, predominantly subpleural and located in the lower lobes, and diffuse interlobular septal thickening and peribronchial thickening. The patient underwent bronchoscopy and bronchoalveolar lavage (BAL) was obtained. Cytospin smears were diagnostic for a low-grade adenocarcinoma. Clinically, the patient had elevated serum prostate-specific antigen (PSA) levels greater than 5,000 ng/mL. Because of this, immunocytochemistry for PSA was performed which was positive, confirming the diagnosis of metastatic prostatic adenocarcinoma. This unusual case of metastatic adenocarcinoma of the prostate first diagnosed by BAL highlights the significance of available clinical information and the use of immunocytochemistry for proper diagnosis. |
| Databáze: | OpenAIRE |
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