A cost analysis of the treatment of patients with post-thrombotic syndrome in Brazil
| Autor: | Gilson Roberto Araujo, Marise Gomes, Liberato Karaoglan de Moura, Flavia Dietrich-Neto, Eduardo Ramacciotti, Jackson Silveira Caiafa, Eduardo Toledo de Aguiar, Ana Truzzi |
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| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Deep vein Low molecular weight heparin Postphlebitic Syndrome macromolecular substances Internal medicine Statistical significance otorhinolaryngologic diseases medicine Humans Prospective Studies Venous Thrombosis Vascular disease business.industry Incidence (epidemiology) Health Care Costs Hematology medicine.disease Thrombosis Surgery Hospitalization carbohydrates (lipids) stomatognathic diseases medicine.anatomical_structure Costs and Cost Analysis bacteria Observational study business Brazil Post-thrombotic syndrome |
| Zdroj: | Thrombosis Research. 118:699-704 |
| ISSN: | 0049-3848 |
| DOI: | 10.1016/j.thromres.2005.12.005 |
| Popis: | Introduction Post-thrombotic syndrome (PTS) occurs in 15–50% of patients with deep vein thrombosis (DVT), and is associated with substantial medical costs. This prospective observational study investigated the costs associated with the treatment of PTS in Brazil. Materials and methods A total of 157 patients diagnosed with PTS and with a history of DVT were recruited from nine centers in Brazil. The costs of investigations and treatment for PTS over a 1-year follow-up period were analyzed. Ninety patients were available for this analysis. Results Of the 90 patients, 17 had mild-to-moderate PTS, and 73 had severe PTS. The patients with severe PTS tended to undergo more investigations and hospitalizations for PTS than those with mild-to-moderate PTS, although the differences between the two groups did not reach statistical significance. The mean annual cost of treating PTS in Brazilian Reais was R$1214 (US$426) for mild-to-moderate PTS and R$3386 (US$1188) for severe PTS. The difference was mainly due to significantly higher hospitalization costs in patients with severe PTS (R$704/US$247 vs. R$0; p =0.044). Conclusion These results suggest that PTS imposes substantial demands on health care resources in Brazil. The implementation of effective thromboprophylactic strategies could significantly reduce the incidence of DVT, and hence of PTS, potentially resulting in significant cost savings. |
| Databáze: | OpenAIRE |
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