The Effect of Short-Term Cardiac Rehabilitation After Acute Myocardial Infarction on High-Sensitivity C-Reactive Protein
| Autor: | Nusret Čobo, Mišo Šabovič, Barbara Salobir, Borut Jug, Polona Mlakar, Marjeta Tercelj |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Pharmacological therapy Endocrinology Diabetes and Metabolism medicine.medical_treatment Myocardial Infarction law.invention Randomized controlled trial law Internal medicine Internal Medicine medicine Humans cardiovascular diseases Myocardial infarction Physical Therapy Modalities Aged Lipoprotein cholesterol Postoperative Care Rehabilitation biology business.industry Smoking C-reactive protein nutritional and metabolic diseases Middle Aged medicine.disease Combined Modality Therapy Coronary heart disease C-Reactive Protein Treatment Outcome Cardiology biology.protein Metabolic syndrome business |
| Zdroj: | Metabolic Syndrome and Related Disorders. 12:149-155 |
| ISSN: | 1557-8518 1540-4196 |
| DOI: | 10.1089/met.2013.0038 |
| Popis: | High-sensitivity C-reactive protein (hsCRP) is an important biomarker of risk for coronary heart disease morbidity and mortality. We investigated the influence of short-term cardiac rehabilitation (CR) after acute myocardial infarction (AMI) on values of hsCRP and classical risk factors, including metabolic syndrome.hsCRP and classical risk factors were measured before and after completed 2-week CR program in 30 men after AMI. The comparison group comprised 30 age-balanced healthy men, with no risk factors for coronary heart disease.As expected, in comparison to healthy individuals, patients had higher values of hsCRP; furthermore, smokers had significantly higher hsCRP values than nonsmokers. Patients had more expressed markers of metabolic syndrome and due to pharmacological therapy lower blood pressure, total cholesterol and low-density lipoprotein cholesterol (LDL-C). After CR was completed, a significant drop in hsCRP (P=0.006) and improvement of metabolic syndrome parameters (lower body mass index, blood pressure, LDL-C, triglycerides) was observed in nonsmokers, whereas no such changes occurred in smokers.Our study revealed that hsCRP and metabolic syndrome parameters can be substantially reduced by a 2-week CR program; however, this effect is present only in nonsmokers. Thus, all patients entering the CR program after AMI should be advised to quit smoking before entering the program to achieve optimal benefits. |
| Databáze: | OpenAIRE |
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