Interfractional diaphragmatic position variation according to stomach volume change during respiratory-gated radiotherapy for hepatocellular carcinoma
| Autor: | Kil Jong Yu, Kwang Min Kim, Byungdo Park, Jee-Hoon Park, Ki Mun Kang, Tae Gyu Kim, Yun Gyu Song, Hyoun Wook Lee, Sanggoon Shim |
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| Rok vydání: | 2021 |
| Předmět: |
Cone beam computed tomography
Carcinoma Hepatocellular medicine.medical_treatment Diaphragm Diaphragmatic breathing medicine Humans Respiratory system Image-guided radiation therapy Retrospective Studies business.industry Stomach Radiotherapy Planning Computer-Assisted Liver Neoplasms Radiotherapy Dosage General Medicine Cone-Beam Computed Tomography medicine.disease Diaphragm (structural system) Radiation therapy medicine.anatomical_structure Hepatocellular carcinoma Nuclear medicine business Radiotherapy Image-Guided |
| Zdroj: | Medical physicsREFERENCES. 48(9) |
| ISSN: | 2473-4209 |
| Popis: | PURPOSE We evaluated the correlation between stomach volume change and interfractional baseline shifts of the diaphragm in image-guided radiotherapy (IGRT) for hepatocellular carcinoma (HCC). MATERIALS AND METHODS Twenty-four patients with HCC underwent ten fractions of IGRT, and a total of 240 cone beam computed tomography (CBCT) and on-board imager (OBI) kV image sets were acquired. These image sets were retrospectively analyzed. Baseline shifts of the diaphragm relative to bone and stomach volume change ratios were evaluated using four-dimensional simulation CT, kV image, and CBCT images. Associations between baseline shifts and patient physiologic factors were investigated. RESULTS The average baseline shift of the diaphragm in the superior-inferior (SI) direction was 1.5 mm (standard deviation 4.6 mm), which was higher than the shift in other directions (0.7, 2.0 mm and 0.9, 2.6 mm in right-left (RL) and anterior-posterior (AP) directions, respectively). Interfractional baseline shifts of the diaphragm in the SI and AP directions were positively correlated with the stomach volume change ratio (Pearson's r: 0.416 and 0.302, p-value |
| Databáze: | OpenAIRE |
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