Laboratory diagnostics, phylogenetic analysis and clinical outcome of a subcutaneous Mycoleptodiscus indicus infection in an immunocompetent cat
| Autor: | Christina Anderson, Susan Sanchez, Paula M. Krimer, Grazieli Maboni, Rodrigo P. Baptista, Ana Lorton |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Antifungal Agents Hypha Fungal culture Case Report Fungus Cat Diseases Subcutaneous infection Microbiology Feline Subcutaneous Tissue Ascomycota Cytology Forelimb Animals Mycoleptodiscus indicus Fluconazole Phylogeny Phylogenetic analysis lcsh:Veterinary medicine General Veterinary Phylogenetic tree biology Soft Tissue Infections Animal disease Traumatic implantation General Medicine biology.organism_classification Treatment Outcome Mycoses Lameness Cats lcsh:SF600-1100 Immunocompetence |
| Zdroj: | BMC Veterinary Research, Vol 15, Iss 1, Pp 1-7 (2019) BMC Veterinary Research |
| ISSN: | 1746-6148 |
| Popis: | Background Mycoleptodiscus indicus is a dematiaceous hyphomycete fungus found on plant leaves. It has been rarely reported as a cause of human or animal disease, possibly because it is difficult to culture and identify from clinical specimens. Infections are presumably acquired by traumatic implantation. Case presentation An 8-year-old non-immunosuppressed cat from Georgia, USA, presented with a left front leg swelling without lameness. Cytology from a fine needle aspirate revealed pyogranulomatous inflammation with both cytoplasmic and extracellular fungal elements. There were septate hyphae with irregularly sized segments, non-staining uneven walls, and rounded yeast-like forms from which longer hyphae arose in a hub-and-spoke pattern. A mold was isolated on agar from a fine needle aspirate collected 1 week later and identified as M. indicus by morphology, DNA sequencing and phylogenetic analysis. The cat recovered completely and uneventfully with antifungal treatment. Conclusions We report a previously undescribed presentation of M. indicus causing a subcutaneous infection in a cat with successful antifungal treatment. In this study we highlight the potential of M. indicus to infect immunocompetent animals, and the veterinary medical community should be aware of its unusual but characteristic clinical, microbiological and cytologic presentation. |
| Databáze: | OpenAIRE |
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