Successful treatment of an infected wound in infants by a combination of negative pressure wound therapy and arginine supplementation
| Autor: | Tomoaki Taguchi, Yoichiro Oka, Toshiro Hara, Mika Wada, Hiroki Kai, Shinichi Hirose, Sadako Yamaguchi, Akinori Iwasaki, Kouji Masumoto, Tsuyoshi Kusuda, Kouji Nagata |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Combination therapy Endocrinology Diabetes and Metabolism medicine.medical_treatment Arginine Enteral administration Negative-pressure wound therapy Surgical Wound Dehiscence Medicine Combined Modality Therapy Humans Medical nutrition therapy Pressure Ulcer Nutrition and Dietetics integumentary system business.industry Wound dehiscence Colostomy Infant Newborn Infant medicine.disease Gastrostomy Surgery Treatment Outcome Anesthesia Child Preschool Dietary Supplements Female business Negative-Pressure Wound Therapy Follow-Up Studies |
| Zdroj: | Nutrition (Burbank, Los Angeles County, Calif.). 27(11-12) |
| ISSN: | 1873-1244 |
| Popis: | Objective Wound dehiscence caused by surgical site infection (SSI) presents a complicated problem. Negative pressure wound therapy (NPWT) was developed to treat wound dehiscence. Nutritional treatment using arginine has also been recently shown to be effective for the treatment of pressure ulcers. Therefore, wound complications due to SSI were treated using NPWT combined with nutritional therapy with an arginine-rich supplement (ARS). Methods Six pediatric patients with wound dehiscence due to SSI received this combined therapy. Results The average age of the patients was 12.2 mo. The operations that these patients underwent included laryngotracheal separation, radical operation for spinal bifida, gastrostomy, colostomy, anorectoplasty, and tumor extirpation. A local wound infection induced wound dehiscence in all patients. Therefore, NPWT was introduced with an enteral administration of ARS. All wounds completely healed within 1 mo after the introduction of this combined therapy without any other complications from the NPWT or ARS. A follow-up study at 6 mo after this therapy was completed showed no complications associated with the wounds. Conclusion This combination therapy using NPWT and ARS administration was effective in inducing early healing of infected wound complications after surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect