A Method for Differentiating Nonspecific Irritants from Anti-Inflammatory Agents Using the Carrageenin Abscess Test
| Autor: | Shemano I, R. DeMeo, Beiler Jm, Goldstein S |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Pathology
medicine.medical_specialty Hydrocortisone Croton Oil medicine.drug_class Indomethacin Anti-Inflammatory Agents Carrageenan General Biochemistry Genetics and Molecular Biology Anti-inflammatory Mefenamic Acid Scapula Formaldehyde medicine Animals ortho-Aminobenzoates Kaolin Abscess Aspirin business.industry bacterial infections and mycoses medicine.disease Rats Phenylbutazone Irritants business |
| Zdroj: | Experimental Biology and Medicine. 123:712-715 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-123-31584 |
| Popis: | SummaryA method is described for differentiating between non-specific irritants and clinically effective anti-inflammatory agents using the carrageenin abscess test. Irritants mixed with the carrageenin increased abscess weight at concentrations which reduced abscess weight when injected subcutaneously at a distant site (scapula area). The anti-inflammatory compounds reduced the abscess weight when mixed with the carrageenin at concentrations below or equal to those concentrations effective systemically. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|