Restriction Analysis of N-Acetyltransferase 2 Gene in Caucasian Population of West Siberia

Autor:	A G Akishev, M. V. Nikishina, Liakhovich Vv, V. A. Vavilin, S. I. Makarova, S Kh Degtiarev
Rok vydání:	2004
Předmět:	Genetics Polymorphism (computer science) Point mutation medicine Coding region Biology Restriction fragment length polymorphism Caucasian population Lung cancer medicine.disease Gene Human genetics
Zdroj:	Scopus-Elsevier
ISSN:	1022-7954
Popis:	Restriction analysis of the NAT2 gene was carried out in inhabitants of Novosibirsk. Polymorphism of this gene for nine known point mutations was studied in a sample of Novosibirsk residents consisting of 109 healthy Caucasians. The frequencies of these mutations did not significantly differ from the frequencies reported for Caucasian populations of other countries. In 79 patients with lung cancer, a region of the NAT2 gene that includes 29.7% of the coding sequence was analyzed for the new mutations by the RFLP analysis. No new mutations were found in this group.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd258ac4b8fe46facf792477c30638c2 https://doi.org/10.1023/b:ruge.0000048672.78131.8e Zobrazit plný text záznamu Full text from SpringerLink