Cytotoxic limonoids from the root bark of Dictamnus angustifolius
| Autor: | Bing Wang, Jianbo Sun, Jing-Yu Liang, Li Chen, Ben-Qin Tang, Qiangqiang Li |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Limonins
Stereochemistry 010402 general chemistry 01 natural sciences Plant Roots HeLa Cell Line Tumor Drug Discovery Cytotoxic T cell Humans Dictamnus Pharmacology biology Molecular Structure 010405 organic chemistry Chemistry General Medicine biology.organism_classification Antineoplastic Agents Phytogenic 0104 chemical sciences visual_art visual_art.visual_art_medium Plant Bark Bark Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Fitoterapia. 115 |
| ISSN: | 1873-6971 |
| Popis: | Three novel limonoids, dictangustone G (1), dictangustone H (2), and dictangustone I (3) were isolated from the root bark of Dictamnus angustifolius. Their structures were elucidated on the basis of detailed spectroscopic analysis including UV, IR, HRESIMS, 1D and 2D NMR spectroscopic experiments. Compounds 1–3 were evaluated for their cytotoxic activities using Hela, A549, MCF7, and LN229 cell lines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect