Characterization of a Novel Lytic Protein Encoded by the Bacillus cereus E33L Gene ampD as a Bacillus anthracis Antimicrobial Protein
| Autor: | Feliza Bourguet, Brian Souza, Angela K. Hinz, Matthew A. Coleman, Paul J. Jackson |
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| Rok vydání: | 2012 |
| Předmět: |
Colony Count
Microbial Bacillus cereus Public Health Microbiology Bacterial genome size Applied Microbiology and Biotechnology Microbiology Amidase chemistry.chemical_compound Bacteriolysis Anti-Infective Agents Bacterial Proteins Biosynthesis Enzyme Stability N-acetylmuramoyl-L-alanine amidase Gene Microscopy Microbial Viability Ecology biology Protein Stability fungi N-Acetylmuramoyl-L-alanine Amidase biology.organism_classification Bacillus anthracis Lytic cycle Biochemistry chemistry Food Science Biotechnology |
| Zdroj: | Applied and Environmental Microbiology. 78:3025-3027 |
| ISSN: | 1098-5336 0099-2240 |
| DOI: | 10.1128/aem.06906-11 |
| Popis: | Lytic proteins encoded by bacterial genomes have been implicated in cell wall biosynthesis and recycling. The Bacillus cereus E33L ampD gene encodes a putative N -acetylmuramoyl- l -alanine amidase. This gene, expressed in vitro , produced a very stable, highly active lytic protein. Very low concentrations rapidly and efficiently lyse vegetative Bacillus anthracis cells. |
| Databáze: | OpenAIRE |
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