Functional outcomes in patients with facial dysostosis and severe upper airway obstruction
| Autor: | P. P.J.M. van der Plas, Irene M.J. Mathijssen, Sarah L. Versnel, Eppo B. Wolvius, Koen F.M. Joosten, Maarten J. Koudstaal, Bas Pullens, S. Yang, Marloes Streppel |
|---|---|
| Přispěvatelé: | Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery and Hand Surgery, Otorhinolaryngology and Head and Neck Surgery, Pediatrics |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty business.industry medicine.medical_treatment Retrospective cohort study 030206 dentistry Airway obstruction medicine.disease 03 medical and health sciences Malnutrition 0302 clinical medicine Parenteral nutrition Otorhinolaryngology 030220 oncology & carcinogenesis medicine Distraction osteogenesis Surgery Oral Surgery Craniofacial Presentation (obstetrics) business SDG 2 - Zero Hunger Treacher Collins syndrome |
| Zdroj: | International Journal of Oral and Maxillofacial Surgery, 50(7), 915-923. Churchill Livingstone |
| ISSN: | 0901-5027 |
| Popis: | An increased risk of upper airway obstruction (UAO) is seen in up to 95% of patients with facial dysostosis. Secondary to respiratory problems are feeding difficulties and increased nutritional requirements. Little has been described regarding these outcomes in this patient population. Hence, a retrospective cohort study was performed to gather data on functional outcomes. Eighteen patients with facial dysostosis and severe UAO were included. The median follow-up time was 3.42 years. A tracheostomy tube was placed in 13 patients, of whom 10 subsequently underwent mandibular distraction. Three of the five patients without a tracheostomy underwent mandibular distraction as the primary surgical treatment; the remaining two patients were treated conservatively with oxygen supplementation. At presentation, 13 patients had feeding difficulties. Overall malnutrition was present in 16 patients during follow-up. At the end of follow-up, severe UAO was present in 12 patients, feeding difficulties in seven patients, and malnutrition in four patients, while two patients died. In conclusion, patients with facial dysostosis have a high prevalence of severe UAO, feeding difficulties, and malnutrition. Importantly, mandibular distraction has limited success in treating severe UAO in these patients. Close follow-up by a specialized craniofacial team is of paramount importance to manage the long-term consequences. |
| Databáze: | OpenAIRE |
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