Pigs as a potential source of emerging livestock-associated Staphylococcus aureus in Africa: a systematic review
| Autor: | Andrew Frey, Hideaki Higashi, Edgar Simulundu, Bernard M. Hang’ombe, Geoffrey Kwenda, Panji Nkhoma, Matthew Bates, Mulemba Tillika Samutela |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Male Methicillin-Resistant Staphylococcus aureus Veterinary medicine Staphylococcus aureus Farms Livestock Swine 030106 microbiology Virulence Infectious and parasitic diseases RC109-216 Biology medicine.disease_cause Disease cluster Antimicrobial resistance 03 medical and health sciences 0302 clinical medicine Antibiotic resistance parasitic diseases medicine Infection control Animals Potential source 030212 general & internal medicine C521 Medical Microbiology General Medicine Staphylococcal Infections C522 Veterinary Microbiology Infectious Diseases One Health Carriage Livestock-associated-MRSA Africa Systematic review Pigs C520 Medical and Veterinary Microbiology |
| Zdroj: | International Journal of Infectious Diseases, Vol 109, Iss, Pp 38-49 (2021) |
| ISSN: | 1201-9712 |
| Popis: | Objective To assess the emergence of livestock-associated Staphylococcus aureus including methicillin-resistant S. aureus (MRSA) in the pig and pork production systems in Africa for the past two decades. Methods PubMed and African Journals OnLine were searched for relevant primary studies from 2000 to 2019 using standardized key words. In total, 19 eligible articles were included in this review. Results The prevalence of S. aureus including MRSA ranged from 0% to 55% among live pigs and raw pork, and from 9.4% to 30.8% among pig farm and abattoir workers. Risk factors associated with S. aureus carriage among workers were: male gender, working in an abattoir, and medical-related occupation of a household member. S. aureus and MRSA from pigs and pork production systems in Africa are potentially pathogenic with diverse spa types and clonal complexes, with genes encoding antimicrobial resistance, heavy metal resistance, and virulence factors including secreted and enterotoxins, proteases and immune evasion cluster. The typical livestock-associated S. aureus CC398 and mecC genes were reported in two studies. Conclusion Pigs are a potential source of the emerging livestock-associated S. aureus in Africa. Continued monitoring using a ‘One Health’ approach is recommended for effective infection prevention and control of these infections in Africa. |
| Databáze: | OpenAIRE |
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