Transfusion practice blind spot in para-Bombay: A case report
| Autor: | Mohd Redzuan Abdullah, Nor Hafizah Ahmad, Afif Alam Faizli, Siti Salmah Noordin, Chin Jian Lee |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Direct coombs test
Male medicine.medical_specialty Saliva business.industry Blind spot RhD positive Hematology 030204 cardiovascular system & hematology Middle Aged Gastroenterology ABO Blood-Group System 03 medical and health sciences Blood grouping 0302 clinical medicine ABO blood group system Internal medicine medicine Humans Blood Transfusion business Packed red blood cells Antibody screening 030215 immunology |
| Zdroj: | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 60(3) |
| ISSN: | 1473-0502 |
| Popis: | H-deficient phenotype individuals with absent or weak anti-H activity may remain undetected on standard routine blood grouping. We report a case of a 59-year-old-man presented with symptomatic anaemia secondary to upper gastrointestinal bleed with haemoglobin level of 68 g/L who required two units of packed red blood cells. He was previously grouped as O Rh D positive and had a history of uneventful multiple blood transfusions. His latest pre-transfusion investigations showed ABO discrepancy between forward and reverse blood grouping, pan-agglutination in both antibody screening and identification with negative direct Coombs test and autocontrol. Further testing including anti-H lectin test and saliva secretor study confirmed that the patient blood group was para-Bombay B RhD positive. This case highlights that the para-Bombay phenotype can be mistakenly labelled as "O" if further investigations are not performed. |
| Databáze: | OpenAIRE |
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