Efficacy of temporary positive expiratory pressure (TPEP) in patients with lung diseases and chronic mucus hypersecretion. The UNIKO® project: a multicentre randomized controlled trial
| Autor: | Ernesto Crisafulli, Daniela Righi, Giorgio Schiavoni, Michele Vitacca, Guido Vagheggini, Vittoria Galimberti, Francesco D'Abrosca, Pier Paolo Cavicchioli, Assunta DeBiase, Enrico Clini, Elena Venturelli, Bruno Balbi, Daniele Berrighi, Luca Bianchi, Mara Paneroni, Nicolino Ambrosino, Michele Zaurino, Andrea Iattoni |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Chronic bronchitis medicine.medical_specialty temporary positive expiratory pressure medicine.medical_treatment Physical Therapy Sports Therapy and Rehabilitation Respiratory Mucosa Rehabilitation Centers law.invention Positive-Pressure Respiration Pulmonary Disease Chronic Obstructive Randomized controlled trial cough law medicine Humans hypersecretion Lung volumes Respiratory system bronchial drainage rehabilitation Bronchitis Aged Analysis of Variance Bronchiectasis Lung Rehabilitation business.industry medicine.disease Surgery Bronchitis Chronic Mucus medicine.anatomical_structure Italy Anesthesia chest physiotherapy COPD bronchiectasis TPEP Female business Inspiratory Capacity |
| Zdroj: | Clinical rehabilitation. 27(4) |
| ISSN: | 1477-0873 |
| Popis: | Objective: To evaluate whether temporary positive expiratory pressure provides benefit in patients with lung diseases and chronic hypersecretion. Design: Single blind multicentre randomized trial. Setting: Five Italian rehabilitation centres. Participants: Ninety-eight patients with chronic obstructive pulmonary disease and/or chronic bronchitis ( n=78), or bronchiectasis ( n=20), with a peak cough expiratory flow >150 l/min and sputum production >30 ml/day, randomly included into two treatment groups. Interventions: For 10 consecutive days, the active group performed twice a day 20-minute cycles of manually assisted breathing techniques in sequence with the addition of 15 minutes of temporary positive expiratory pressure, while the control group was treated by manually assisted breathing techniques alone. Measures: Within and between group changes of arterial oxygenation index, lung volumes and respiratory muscles strength were recorded at enrolment and after 3 and 10 treatment sessions. Pre-to-post treatment change of sputum volume and bronchial encumbrance (Δ-visual analog scale), sputum density and purulence were compared daily within the study period. Results: No significant changes were recorded for the oxygenation index, while dynamic lung volumes and respiratory muscle strength significantly ( P Conclusions: These preliminary data suggest that temporary positive expiratory pressure improves lung volumes and speeds up the improvement of bronchial encumbrance in patients with lung diseases and hypersecretion. |
| Databáze: | OpenAIRE |
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