Hair bundle profiles along the chick basilar papilla
| Autor: | M. G. Dubin, K. E. Ile, R. K. Duncan, J. C. Saunders |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Histology
Stereocilia (inner ear) Short hair Biology Hair Cells Auditory medicine otorhinolaryngologic diseases Basilar papilla Animals Molecular Biology Ecology Evolution Behavior and Systematics integumentary system Cell Biology Anatomy Kinocilium Major duodenal papilla medicine.anatomical_structure Bundle Microscopy Electron Scanning Hair cell sense organs Transduction (physiology) Chickens Developmental Biology Research Article |
| Zdroj: | Journal of anatomy. 198(Pt 1) |
| ISSN: | 0021-8782 |
| Popis: | Cochlear hair cells play a central role in the transduction of sound into neural output. Anatomical descriptions of these cells, and their protruding hair bundles, are of fundamental interest since hair cell transduction is dependent on hair bundle micromechanics and hair bundle micromechanics depends on hair bundle morphology. In this paper, we describe quantitatively changes in the staircase profile of the hair bundle along the apical portion of the chick's basilar papilla. Images of hair cells from 8 discretely dissected segments of the apical 3rd of the basilar papilla were archived, and the profile contour outlined by the tips of the stereocilia was digitised and curves were fitted by linear and power equations. The hair bundles of tall hair cells exhibited both linear and curvilinear profiles, which were equally distributed along the papilla. All short hair cells in our sample had straight contours. The differences in hair bundle shape among the tall hair cells may lead to differential susceptibility to injury and some variance in the current-displacement transduction curves due to differences in the translation of forces throughout the hair bundle. |
| Databáze: | OpenAIRE |
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