TIN-X:target importance and novelty explorer
| Autor: | Larry A. Sklar, Stephan C. Schürer, Tudor I. Oprea, Anna Waller, Jeremy J. Yang, Cristian Bologa, Stephen L. Mathias, Subramani Mani, Daniel C. Cannon, Lars Juhl Jensen, Oleg Ursu |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Statistics and Probability Computer science Association (object-oriented programming) Receptors Cytoplasmic and Nuclear Scientific literature Ontology (information science) Biochemistry Ion Channels Receptors G-Protein-Coupled 03 medical and health sciences 0302 clinical medicine Text mining Computer Graphics Data Mining Humans Disease Molecular Biology Information retrieval business.industry Phosphotransferases Novelty Applications Notes Computer Science Applications Computational Mathematics 030104 developmental biology Computational Theory and Mathematics Biological Ontologies Ontology Data and Text Mining business 030217 neurology & neurosurgery Software |
| Zdroj: | Cannon, D C, Yang, J J, Mathias, S L, Ursu, O, Mani, S, Waller, A, Schürer, S C, Jensen, L J, Sklar, L A, Bologa, C G & Oprea, T I 2017, ' TIN-X : target importance and novelty explorer ', Bioinformatics, vol. 33, no. 16, pp. 2601-2603 . https://doi.org/10.1093/bioinformatics/btx200 Bioinformatics |
| DOI: | 10.1093/bioinformatics/btx200 |
| Popis: | Motivation The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins. Results We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty. Availability and Implementation http://www.newdrugtargets.org |
| Databáze: | OpenAIRE |
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