A Novel Collaborative Community-Based Hepatitis B Screening and Linkage to Care Program for African Immigrants
| Autor: | Kim Nichols, Ellie Carmody, Demetri Blanas, Ponni V. Perumalswami, Hari Shankar, Joan Culpepper-Morgan, Valérie Martel-Laferrière, Andrea D. Branch, Daouda Ndiaye, Mulusew Bekele, Dougles T. Dieterich, Kian Bichoupan |
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| Rok vydání: | 2016 |
| Předmět: |
Microbiology (medical)
Adult Male HBsAg medicine.medical_specialty Carcinoma Hepatocellular Population Black People Emigrants and Immigrants medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Interquartile range Risk Factors Internal medicine Medicine Humans Mass Screening Hepatitis B Vaccines 030212 general & internal medicine Community Health Services Hepatitis B Antibodies education Mass screening Hepatitis Hepatitis B virus education.field_of_study business.industry Liver Neoplasms virus diseases Odds ratio Hepatitis B Middle Aged medicine.disease digestive system diseases Infectious Diseases Immunology 030211 gastroenterology & hepatology Female New York City business |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 62 |
| ISSN: | 1537-6591 |
| Popis: | BACKGROUND Sub-Saharan African nations have among the highest rates of chronic hepatitis B virus (HBV) infection worldwide, but little is known about HBV infection in African-born persons in the United States. METHODS From October 2011 to July 2013, community-based HBV screenings were conducted targeting persons originating from Africa in New York City. Persons were identified as currently HBV infected (HBsAg positive) or exposed (HBcAb positive). RESULTS Overall, 955 persons were screened for HBV; the median age was 45 years (interquartile range, 35-54 years) and 75.5% were men. Of these, 919 persons had no history of liver disease, of whom 9.6% (n = 88) had current HBV infection and 73.9% (n = 679) had exposure. In logistic regression, older age (odds ratio [OR], 0.97; 95% confidence interval [CI], .94-.99; P < .01) and female sex (OR, 0.35; 95% CI, .14-.75; P < .01) were less likely to be associated with HBV infection, whereas having a mother with hepatitis was associated with infection (OR, 18.8; 95% CI, 2.72-164.65; P < .01). HBV exposure was associated with older age (OR, 1.03; 95% CI, 1.01-1.04; P < .01), whereas female sex (OR, 0.46; 95% CI, .33-.66; P < .01) and history of blood transfusion (OR, 0.43; 95% CI, .22-.83; P = .01) were negatively associated. A patient navigator linked 97% of infected persons to care. Eleven persons were recommended for treatment, of whom 9 (82%) started therapy. Three persons were diagnosed with hepatocellular carcinoma on the first screening ultrasound. CONCLUSIONS The high burden of HBV infection among African immigrants in the United States underscores a need for continued screening and linkage to care in this at-risk population. |
| Databáze: | OpenAIRE |
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