Fibromyalgia as a cause of uncontrolled asthma: a case-control multicenter study

Autor: Eva Martínez-Moragón, Isabel Torres, Carles Sabadell, Julio Delgado, Marina Blanco-Aparicio, Ana M. Muñoz-Fernandez, Isabel Urrutia, Xavier Casas, Pilar Cebollero, Belen Hinojosa, Ana Rosado, Santiago Quirce, Vicente Plaza
Rok vydání: 2017
Předmět:
Zdroj: Current medical research and opinion. 33(12)
ISSN: 1473-4877
Popis: Fibromyalgia can affect the control of asthma when both diseases are present in a single patient.To characterize asthma in patients with concomitant fibromyalgia to assess whether fibromyalgia is an independent factor of asthma severity that influences poor asthma control. We also evaluated how dyspnea is perceived by patients in order to demonstrate that alterations in the perception of airway obstruction may be responsible for poor asthma control.This was a cross-sectional case-control multicenter study, in which 56 patients in the asthma and fibromyalgia group were matched to 36 asthmatics by sex, approximate age, and asthma severity level. All patients were women. Study variables included the Asthma Control Test (ACT), the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), the Nijmegen hyperventilation syndrome questionnaire, the Hospital Anxiety and Depression Scale, and perception of dyspnea after acute bronchoconstriction.Although patients in both study groups showed similar asthma severity and use of anti-asthmatic drugs, patients in the asthma and fibromyalgia group showed lower scores on the ACT and MiniAQLQ questionnaires, and higher scores of anxiety and depression as well as hyperventilation compared to asthma patients without fibromyalgia. All these differences were statistically significant.Fibromyalgia in patients with asthma influences poor control of the respiratory disease and is associated with altered perception of dyspnea, hyperventilation syndrome, high prevalence of depression and anxiety, and impaired quality of life.Fibromyalgia may be considered a risk factor for uncontrolled asthma in patients suffering from asthma and fibromyalgia concomitantly.
Databáze: OpenAIRE