Gamete development in malaria parasites: bicarbonate-dependent stimulation by pH in vitro
| Autor: | Richard Carter, Mary M. Nijhout |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Plasmodium
Partial Pressure Bicarbonate Stimulation Biology Plasmodium gallinaceum chemistry.chemical_compound Gametocyte medicine Animals Gametogenesis Carbon Dioxide Hydrogen-Ion Concentration medicine.disease biology.organism_classification Cell biology Bicarbonates Blood Infectious Diseases medicine.anatomical_structure chemistry Flagella Immunology Gamete Animal Science and Zoology Parasitology Energy source Chickens Malaria |
| Zdroj: | Parasitology. 76:39-53 |
| ISSN: | 1469-8161 0031-1820 |
| DOI: | 10.1017/s0031182000047375 |
| Popis: | SummaryGametogenesis in Plasmodium gallinaceum involves bicarbonate-dependent processes and requires a continuous supply of glucose (presumably as an energy source). Emergence and exflagellation of gametocytes, in vitro, occur independently of the CO2 tension but are rigidly correlated with the pH of the external medium. In bicarbonate-saline gametogenesis is initiated only if the pH exceeds 7·7. Our results suggest that gamete development of malaria parasites is stimulated when infected blood is exposed to air because the decrease in the CO2 tension of the blood causes its pH to rise. |
| Databáze: | OpenAIRE |
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