Effects of aspirin combined with cilostazol on thromboangiitis obliterans in diabetic patients

Autor:	Qinglin Zhou, Wenchen Guo, Shaomei Zhang, Peixia Shi, Yan Gao, Jun Yong
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Cancer Research medicine.medical_specialty aspirin 030204 cardiovascular system & hematology Thromboangitis Obliterans 01 natural sciences Gastroenterology Nitric oxide 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine inflammatory factors Immunology and Microbiology (miscellaneous) Internal medicine thromboangitis obliterans medicine Inflammatory factors 0101 mathematics Aspirin business.industry Cancer Interleukin General Medicine Articles medicine.disease Molecular medicine Cilostazol 010101 applied mathematics chemistry business cilostazol medicine.drug
Zdroj:	Experimental and Therapeutic Medicine
ISSN:	1792-1015 1792-0981
Popis:	The present study explored the effects of aspirin combined with cilostazolin in the treatment of diabetic patients with thromboangiitis obliterans and the effects on the related inflammatory factors. A total of 90 diabetic patients with thromboangiitis obliterans admitted to Weifang People's Hospital from August 2015 to June 2017 were selected and divided into the control group (n=45) and the combination group (n=45). Patients in the control group were given aspirin, and those in the combination group were given aspirin combined with cilostazol. Before treatment and 6 weeks after treatment, the clinical data including ankle-brachial index (ABI), 6-min walk test (6MWT) and test data including serum inflammatory factors interleukin (IL)-8, IL-6 and matrix metalloprotease (MMP)-2 and MMP-9 of the two groups were collected for quantitative and statistical analysis. Compared with those in the control group, the ABI and 6MWT in the combination group could be effectively reduced, and the differences were statistically significant (P
Databáze:	OpenAIRE
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