Drug-induced sleep endoscopy findings in surgically-naïve obese vs non-obese children
| Autor: | Michael Davis, Sveta Karelsky, Paul D. Allen, Margo McKenna, Sarah Lookabaugh, Amanda Didas, John Faria |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Pediatric Obesity medicine.medical_treatment Polysomnography Adenoid Adenoidectomy Internal medicine medicine Humans Prospective Studies Prospective cohort study Child Retrospective Studies business.industry Endoscopy General Medicine Airway obstruction medicine.disease Tonsillectomy Obstructive sleep apnea medicine.anatomical_structure Otorhinolaryngology Pharmaceutical Preparations Child Preschool Pediatrics Perinatology and Child Health Airway business Sleep Cohort study |
| Zdroj: | International journal of pediatric otorhinolaryngology. 138 |
| ISSN: | 1872-8464 |
| Popis: | To determine if drug-induced sleep endoscopy (DISE) findings are different in obese versus non-obese pediatric patients with obstructive sleep apnea (OSA) or sleep-disordered breathing (SDB).Prospective, observational cohort study from June 2017 to June 2018 at a tertiary academic pediatric medical center that included surgically-naïve children ages 2-12 with diagnoses of OSA or sleep-disordered breathing. Subjects with a known diagnosis of craniofacial syndromes, genetic disorders, prior adenoidectomy or tonsillectomy, or chronic tonsillitis as the indication for surgery were excluded. Two groups were assessed for patterns of obstruction based on DISE videos at each anatomic airway level using a previously published DISE scoring system. The groups included obese subjects (BMI ≥ 95th percentile) and non-obese controls (BMI85th percentile). Each video was graded by two blinded, fellowship-trained Pediatric Otolaryngologists.Fifty-one patients were included, 26 non-obese and 25 obese. Based on anatomic airway level, there was no statistically significant difference in airway obstruction at the velum (p = 0.134), adenoid (p = 0.592), lateral pharyngeal walls (p = 0.867), tongue base (p = 0.977), or supraglottis (p = 0.428) between obese and non-obese children.Our prospective study did not associate severity of obstruction with obesity status based on anatomic airway levels. Further studies are needed to elucidate the etiology of the high rate of persistent obstructive sleep apnea in obese children. |
| Databáze: | OpenAIRE |
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