Using Laser-Doppler Flowmetry to Evaluate the Therapeutic Response in Dentin Hypersensitivity
| Autor: | Diana Lungeanu, Mariana Miron, Emilia Ogodescu, Edmond Ciora, Carmen Todea |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Dentin Desensitizing Agents
Health Toxicology and Mutagenesis Dentistry microcirculation lcsh:Medicine Article law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial stomatognathic system law Laser-Doppler Flowmetry Medicine Humans Verbal Rating Scale Single-Blind Method outcome assessment business.industry lcsh:R Public Health Environmental and Occupational Health Repeated measures design Reproducibility of Results 030208 emergency & critical care medicine 030206 dentistry Blood flow dentin hypersensitivity Laser Doppler velocimetry Dentin Sensitivity medicine.disease laser Doppler flowmetry therapeutic research Fluoride gel stomatognathic diseases Dentin hypersensitivity Pulp (tooth) business |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 17, Iss 8787, p 8787 (2020) International Journal of Environmental Research and Public Health Volume 17 Issue 23 |
| ISSN: | 1661-7827 1660-4601 |
| Popis: | Dentin hypersensitivity (DH) is a common medical condition with underreported prevalence and it is difficult to quantify. This study aimed to investigate whether assessing dental pulp vascular micro-dynamics by laser-Doppler flowmetry (LDF) would be functional for therapeutic evaluation, in contrast to a verbal rating scale (VRS). A split-mouth single-blind randomized study was conducted on seven patients and a total of 36 teeth. Two DH therapeutic methods were employed: (i) fluoride gel (ii) Nd:YAG radiation combined with fluoride gel. For each tooth, five consecutive LDF determinations of pulp blood flow were made (before and immediately after desensitizing treatment, then after 24 h, 7 days, and 1 month), and the VRS was applied each time. Spearman&rsquo s correlation was applied for concurrent validation. Two-way (treatment and patient) repeated measures ANOVA full factorial was applied, followed by Tukey&rsquo s post-hoc comparisons and Pillai&rsquo s trace multivariate statistic. While VRS scores had moderate reliability, LDF could objectively estimate treatment effects. Based on partial eta-squared values, treatment and patient characteristics were estimated to explain about 84% and 50% of the variability, respectively. In conclusion, LDF is an objective technique that can quantitatively assess DH evolution, and it is effective in reliably monitoring oral health therapeutic interventions. |
| Databáze: | OpenAIRE |
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