A Double Pituitary Adenoma Presenting as a Prolactin-secreting Tumor with Partial Response to Medical Therapy. Case report
| Autor: | Eva Horvath, H. S. Smyth, Kalman Kovacs, Dominic Rosso, Claire Coire |
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| Rok vydání: | 2010 |
| Předmět: |
Adenoma
Adult Male Pathology medicine.medical_specialty Cabergoline Neurofibromatosis 1 endocrine system diseases Endocrinology Diabetes and Metabolism Antineoplastic Agents Gonadotrophs Gonadotropic cell Dopamine agonist Neurosurgical Procedures Breast Neoplasms Male Pathology and Forensic Medicine Neoplasms Multiple Primary Endocrinology Microscopy Electron Transmission Pituitary adenoma Humans Medicine Combined Modality Therapy Prolactinoma Ergolines business.industry Neoplasms Second Primary General Medicine medicine.disease digestive system diseases Prolactin stomatognathic diseases business medicine.drug |
| Zdroj: | Endocrine Pathology. 21:135-138 |
| ISSN: | 1559-0097 1046-3976 |
| Popis: | Double pituitary adenomas are difficult to recognize pre-operatively as only a single mass may be appreciated on imaging. We present herein a giant prolactin-secreting pituitary adenoma in a middle-aged man that had responded partially to dopamine agonist therapy. The excised specimen demonstrated a double adenoma. The prolactin-producing one displayed the expected morphological changes resulting from medical therapy, while the other, a gonadotroph adenoma, did not. The failure of tumor shrinkage can be attributed to the presence of a double adenoma, a previously unreported cause of failure of medical therapy in prolactinoma. |
| Databáze: | OpenAIRE |
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