Respiratory Inflammation Among Workers Exposed to Airborne Dust With Endotoxins in a Coffee Curing Factory

Autor: Christina Pehrson, Magne Bråtveit, Bente E. Moen, Yohana Mashalla, Akwilina V. Kayumba, Gloria Sakwari, Lennart Larsson, Simon H. D. Mamuya
Rok vydání: 2012
Předmět:
Zdroj: Journal of Occupational & Environmental Medicine. 54:847-850
ISSN: 1076-2752
DOI: 10.1097/jom.0b013e318250ca24
Popis: OBJECTIVE: To study dust exposure and inflammatory reactions in the respiratory tract among coffee curing workers in Tanzania. METHODS: A cross-sectional study was conducted in a Tanzanian coffee curing factory. Coffee workers (n = 15) were compared with unexposed controls (n = 18); all workers were nonsmokers. Exhaled nitric oxide was examined using an electrochemistry-based NIOX MINO device. Personal air samples were analyzed for total dust and endotoxins, using gravimetric analysis and the chromogenic Limulus amebocyte lysate endpoint assay, respectively. RESULTS: Total dust levels ranged from 0.2 to 27.9 mg/m, and endotoxin levels ranged from 42 to 75,083 endotoxin units/m. Concentrations of exhaled nitric oxide, analyzed by linear regression and adjusted for age (β = 0.57; 95% confidence interval, 0.08 to 1.06; P = 0.02), was higher among coffee workers than among the control group. CONCLUSION: The results indicate a relationship between the coffee dust and signs of respiratory inflammation. (Less)
Databáze: OpenAIRE