Role of selected parameters and integral indices of treadmill test in the assessment of complication risk among patients with chronic coronary heart disease
| Autor: | Martsevich, S. Yu, Tolpygina, S. N., Malysheva, A. M., Polyanskaya, Yu N., Hofmann, E. A., Lerman, O. V., Mazaev, V. P., Alexander Deev |
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| Předmět: |
medicine.medical_specialty
business.industry Incidence (epidemiology) medicine.medical_treatment Percutaneous coronary intervention treadmill test Chest pain Revascularization medicine.disease RC666-701 Internal medicine medicine Cardiology Diseases of the circulatory (Cardiovascular) system ST segment Myocardial infarction Treadmill medicine.symptom Cardiology and Cardiovascular Medicine business integral indices Depression (differential diagnoses) chronic coronary heart disease complication risk assessment |
| Zdroj: | Scopus-Elsevier Кардиоваскулярная терапия и профилактика, Vol 11, Iss 2, Pp 44-52 (2012) |
| Popis: | Aim. To identify the value of selected parameters and integral indices of treadmill test (TT), such as Duke Treadmill Score (DTS), Centre for Preventive Medicine index (CPMI), and modified CPMI, in the assessment of cardiovascular complication (CVC) risk among patients with chronic coronary heart disease (CCHD). Material and methods. The study included all consecutive patients with the admission diagnosis of CCHD (n=260), who underwent coronary angiography (CAG) and TT in the period from January 1st 2004 to December 31st 2007, and were permanent residents of Moscow City or Moscow Region. Primary end-point was death from all causes; non-fatal CVC included acute myocardial infarction, acute cerebrovascular accident, and revascularization (percutaneous coronary intervention or coronary artery bypass graft surgery). Results. The mean time to the development of primary end-point was 3,2 years; it total, it was registered in 71 patients (32,0 %). The incidence of primary end-point was higher in patients with ST segment depression ≥1 mm at TT, positive TT result, or chest pain development during the test. Achievement of target heart rate and TT time ≥12 minutes was associated with a better prognosis. In patients with high and intermediate risk by DTS and CPMI, the incidence of primary end-point was higher than in patients with low risk. Modified CPMI demonstrated high correlation with the primary end-point. Conclusion. The highest prognostic value in the assessment of the risk of CCHD complications was demonstrated by TT result, ST segment depression ≥1 mm, TT time, and chronotropic TT response. The role of CPMI and modified CPMI as predictors of CVC risk in CCHD patients was assessed. |
| Databáze: | OpenAIRE |
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