Identification of Shigella flexneri subserotype 1c in rural Egypt
| Autor: | Stephen J. Savarino, Edward M. Lane, Atef M. El-Gendy, Leonard F. Peruski, Nils I. A. Carlin, Bradford A. Kay, Mary M. Mitry, Remon Abu Elyazeed, Nemat El-Ghorab |
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| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
Serotype Diarrhea Rural Population Shigellosis Epidemiology Population Serology Microbiology Shigella flexneri Feces medicine Humans Serotyping education Dysentery Bacillary education.field_of_study Antigens Bacterial biology business.industry Antibodies Monoclonal biology.organism_classification medicine.disease Virology Enterobacteriaceae Antibodies Bacterial biology.protein Egypt Reagent Kits Diagnostic medicine.symptom Antibody business |
| Zdroj: | Journal of clinical microbiology. 37(3) |
| ISSN: | 0095-1137 |
| Popis: | In a population-based study of diarrhea in rural, northern Egypt, 60 Shigella flexneri strains were identified, of which 10 could not be definitively serotyped. Serological analysis with commercial reagents suggested that they were serotype 1, but the strains failed to react with subserotype 1a- or 1b-specific antibodies. All 10 strains reacted with MASF 1c, a monoclonal antibody specific for a provisional S. flexneri subserotype, 1c, first identified in Bangladesh and not previously detected outside of that region. Our results show that S. flexneri subserotype 1c is not unique to Bangladesh and that the inability to detect it may reflect both the limited use of suitable screening methods and the rarity of this subserotype. |
| Databáze: | OpenAIRE |
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