Improved seizure control and regaining cognitive milestones after vagus nerve stimulation revision surgery in Lennox–Gastaut syndrome
| Autor: | Suzanne M. Koudijs, Danny M. W. Hilkman, Joke Creemers, Erwin M. J. Cornips, Hilde M.H. Braakman, Mariette H. J. A. Debeij-van Hall, Sylvia Klinkenberg |
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| Přispěvatelé: | MUMC+: MA Med Staf Spec Neurologie (9), MUMC+: HZC Med Staf Spec Klinische Neurofys (9), Klinische Neurowetenschappen, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Med Staf Spec Neurochirurgie (9) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty genetic structures medicine.medical_treatment Lennox-Gastaut syndrome Status epilepticus Article lcsh:RC321-571 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Seizure control Medicine lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Refractory epilepsy Psychomotor learning Seizure frequency business.industry Cognition medicine.disease Seizure freedom Surgery 030104 developmental biology Neurology Neurology (clinical) Revision surgery medicine.symptom business Nerve segment Vagus nerve stimulation 030217 neurology & neurosurgery Lennox–Gastaut syndrome |
| Zdroj: | Epilepsy and Behavior Case Reports, Vol 10, Iss, Pp 111-113 (2018) Epilepsy & Behavior Case Reports Epilepsy & behavior case reports, 10, 111-113. Elsevier Science |
| ISSN: | 2213-3232 |
| Popis: | We report a child with Lennox–Gastaut syndrome with an increase in seizure frequency and loss of psychomotor skills due to a disintegrated cervical VNS lead, not detected during standard device monitoring. The lead was completely removed and replaced by a new 303 lead on the same nerve segment. After reinitiating VNS, side effects forced us to switch it off, resulting in immediate seizure recurrence. EEG recording demonstrated a non-convulsive status epilepticus that was halted by reinitiating VNS therapy. Thereafter, he remained seizure free for eight months, and regained psychomotor development. Highlights • Routine VNS device monitoring may not always detect lead dysfunction. • Seizure recurrence and loss of psychomotor skills may imply lead dysfunction. • Complete VNS revision may yield excellent results in LGS. • VNS revision can correct clinical deterioration associated with lead dysfunction. |
| Databáze: | OpenAIRE |
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