Electrosynthetic C-F bond cleavage

Autor: Johannes L. Röckl, Emma L. Robertson, Helena Lundberg
Rok vydání: 2022
Předmět:
Zdroj: Organicbiomolecular chemistry. 20(34)
ISSN: 1477-0539
Popis: Fluorinated organic compounds are common among pharmaceuticals, agrochemicals and materials. The significant strength of the C-F bond results in chemical inertness that, depending on the context, is beneficial, problematic or simply a formidable synthetic challenge. Electrosynthesis is a rapidly expanding methodology that can enable new reactivity and selectivity for cleavage and formation of chemical bonds. Here, a comprehensive overview of synthetically relevant electrochemically driven protocols for C-F bond activation and functionalization is presented, including photoelectrochemical strategies.
Databáze: OpenAIRE