Is prostate-specific antigen a potential new marker of androgen excess in polycystic ovary syndrome?
| Autor: | Harika Bodur, Birol Vural, Sebiha Özkan |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty urologic and male genital diseases Follicle-stimulating hormone Sex hormone-binding globulin Insulin resistance Internal medicine medicine Humans Prospective Studies Testosterone Tumor marker biology business.industry Hyperandrogenism Obstetrics and Gynecology Prostate-Specific Antigen medicine.disease Polycystic ovary Prostate-specific antigen Endocrinology Case-Control Studies biology.protein Female business Biomarkers Polycystic Ovary Syndrome |
| Zdroj: | Journal of Obstetrics and Gynaecology Research. 33:166-173 |
| ISSN: | 1447-0756 1341-8076 |
| DOI: | 10.1111/j.1447-0756.2007.00507.x |
| Popis: | Aim: To determine whether serum prostate-specific antigen (PSA) levels are increased in polycystic ovary syndrome (PCOS) and the possibility of PSA to be used as a diagnostic marker of hyperandrogenism in females. Methods: A total of 43 women with PCOS and 43 age-matched healthy females were recruited in this prospective case-control study. The subjects were compared by means of demographic parameters, hormonal and metabolic measures and serum PSA levels. The correlations between this marker and a wide variety of hormonal, biochemical, anthropometric measures were evaluated. Student's t-test, χ2-test and Spearman's correlation analysis were used for the statistical analysis where appropriate. Statistical significance was assumed with a value of P |
| Databáze: | OpenAIRE |
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