Posterior Reversible Encephalopathy Syndrome After Azathioprine Administration in Severe Ulcerative Colitis
| Autor: | Paolo Bocus, Renzo Montanari, Mirko Di Ruscio, Filippo Vernia, Angela Variola, Arianna Massella |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Neurological signs
medicine.medical_specialty medicine.diagnostic_test business.industry Inflammatory Bowel Disease Inflammatory Bowel Diseases Azathioprine Posterior reversible encephalopathy syndrome Magnetic resonance imaging Case Report General Medicine medicine.disease Ulcerative colitis Gastroenterology Discontinuation 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine Medicine 030211 gastroenterology & hepatology business Occipital lobe medicine.drug |
| Zdroj: | ACG Case Reports Journal |
| ISSN: | 2326-3253 |
| Popis: | Posterior reversible encephalopathy syndrome is a rare syndrome characterized by brain edema and neurological symptoms, often resulting from several drugs. Treatment is based on discontinuation, and diagnosis is thus essential. Only 13 cases of posterior reversible encephalopathy syndrome have been reported in inflammatory bowel diseases, and we present the first after azathioprine in adults. A 56-year-old patient with active ulcerative colitis was found unconscious 5 days after the institution of azathioprine. Right-sided hemiplegia was found after the patient regained consciousness. Magnetic resonance imaging showed altered signal associated with diffusion restriction in the occipital lobe and cerebral vasogenic edema. Complete regression of neurological signs occurred after azathioprine discontinuation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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