Reproducibility and evolution of diffusion MRI measurements within the cervical spinal cord in multiple sclerosis
| Autor: | Haykel Snoussi, Benoit Combes, Olivier Commowick, Elise Bannier, Anne Kerbrat, Julien Cohen-Adad, Christian Barillot, Emmanuel Caruyer |
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| Přispěvatelé: | Neuroimagerie: méthodes et applications (EMPENN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-SIGNAL, IMAGE ET LANGAGE (IRISA-D6), Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), University of Texas Health Science Center, The University of Texas Health Science Center at Houston (UTHealth), Département de Radiologie [CHU de Rennes], Université de Rennes (UR), Service de Neurologie [CHU Rennes], CHU Pontchaillou [Rennes], École Polytechnique de Montréal (EPM), Caruyer, Emmanuel |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Multiple Sclerosis
Spinal Cord [SCCO.COMP] Cognitive science/Computer science Image and Video Processing (eess.IV) FOS: Electrical engineering electronic engineering information engineering FOS: Physical sciences [SCCO.COMP]Cognitive science/Computer science Medical Physics (physics.med-ph) Electrical Engineering and Systems Science - Image and Video Processing Physics - Medical Physics Diffusion MRI |
| Zdroj: | ISBI 2022-IEEE International Symposium on Biomedical Imaging ISBI 2022-IEEE International Symposium on Biomedical Imaging, Mar 2022, Kolkata, India. pp.1-5 HAL |
| Popis: | In Multiple Sclerosis (MS), there is a large discrepancy between the clinical observations and how the pathology is exhibited on brain images, this is known as the clinical-radiological paradox (CRP). One of the hypotheses is that the clinical deficit may be more related to the spinal cord damage than the number or location of lesions in the brain. Therefore, investigating how the spinal cord is damaged becomes an acute challenge to better understand and overcome the CRP. Diffusion MRI is known to provide quantitative figures of neuronal degeneration and axonal loss, in the brain as well as in the spinal cord. In this paper, we propose to investigate how diffusion MRI metrics vary in the different cervical regions with the progression of the disease. We first study the reproducibility of diffusion MRI on healthy volunteers with a test-retest procedure using both standard diffusion tensor imaging (DTI) and multi-compartment Ball-and-Stick models. Then, based on the test re-test quantitative calibration, we provide quantitative figures of pathology evolution between M0 and M12 in the cervical spine on a set of 31 MS patients, exhibiting how the pathology damage spans in the cervical spinal cord. Submitted to MICCAI 2018 (Weak Accept and 2 Weak reject) |
| Databáze: | OpenAIRE |
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