Sensitivity and latency of ionising radiation-induced cataract
| Autor: | Elizabeth A. Ainsbury, Stephen Barnard |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Low dose Dose-Response Relationship Radiation Sensory Systems Cataract Ionizing radiation Cellular and Molecular Neuroscience Ophthalmology Induced Cataract medicine.anatomical_structure Risk Factors Internal medicine Lens (anatomy) Radiation Ionizing Lens Crystalline medicine Humans Radiosensitivity Latency (engineering) Radiation protection business Radiation Injuries Low Dose Radiation |
| Zdroj: | Experimental eye research. 212 |
| ISSN: | 1096-0007 |
| Popis: | When managed with appropriate radiation protection procedures, ionising radiation is of great benefit to society. Opacification of the lens, and vision impairing cataract, have recently been recognised at potential effects of relatively low dose radiation exposure, on the order of 1 Gy or below. Within the last 10 years, understanding of the effects of low dose ionising radiation on the lens has increased, particularly in terms of DNA damage and responses, and how multiple radiation or other events in the lens might contribute to the overall risk of cataract. However, gaps remain, not least in the understanding of how radiation interacts with other risk factors such as aging, as well as the relative radiosensitivity of the lens compared to tissues of the body. This paper reviews the current literature in the field of low dose radiation cataract, with a particular focus on sensitivity and latency. |
| Databáze: | OpenAIRE |
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