Short-term effects of glucose and sucrose on cognitive performance and mood in elderly people
| Autor: | L. C. P. G. M. De Groot, N.L. van der Zwaluw, O. van de Rest, Roy P. C. Kessels |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Sucrose subjective memory Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1] blood-glucose Audiology Neuropsychological Tests Placebo Developmental psychology Cognition Double-Blind Method Memory medicine Reaction Time Attention Effects of sleep deprivation on cognitive performance older-adults humans Episodic memory enhancement memory performance Aged VLAG Aged 80 and over Global Nutrition Wereldvoeding Neuro- en revalidatiepsychologie Working memory Neuropsychology and rehabilitation psychology Neuropsychology participants aged 24-81 Plasticity and Memory [DI-BCB_DCC_Theme 3] normative data Crossover study Clinical Psychology Affect Mood Glucose Neurology carbohydrate Female Neurology (clinical) Psychology diabetes-mellitus |
| Zdroj: | Journal of Clinical and Experimental Neuropsychology, 36(5), 517-527 Neuropsychology, Development, and Cognition. Section A, Journal of Clinical and Experimental Neuropsychology, 36, 5, pp. 517-527 Neuropsychology, Development, and Cognition. Section A, Journal of Clinical and Experimental Neuropsychology, 36, 517-527 Journal of Clinical and Experimental Neuropsychology 36 (2014) 5 |
| ISSN: | 1380-3395 |
| Popis: | Item does not contain fulltext In this study we determined the short-term effects of a glucose drink and a sucrose drink compared to a placebo on cognitive performance and mood in elderly people with subjective, mild memory complaints using a randomized crossover study design. In total, 43 nondiabetic older adults with self-reported memory complaints were included. Drinks consisted of 250 ml with dissolved glucose (50 g), sucrose (100 g), or a mixture of artificial sweeteners (placebo). Multiple neuropsychological tests were performed and were combined by means of z scores into four cognitive domains: episodic memory, working memory, attention and information (processing speed), and executive functioning. Mood was assessed with the short Profile of Mood Status (s-POMS) questionnaire. Blood glucose concentrations were measured at five time points to divide participants into those with a better or poorer blood glucose recovery. Performance on the domain of attention and information processing speed was significantly better after consuming the sucrose drink (domain score of 0.06, SD = 0.91) than after the placebo drink (-0.08, SD = 0.92, p = .04). Sucrose had no effect on the other three domains, and glucose had no effect on any of the domains compared to the placebo. When dividing participants into poorer or better glucose recoverers, the beneficial effect of sucrose on attention and information processing speed was only seen in participants with a poorer recovery. After sucrose consumption, depressive feelings and tension were slightly higher than after the placebo. To conclude, 100 g sucrose, but not 50 g glucose, optimized attention and information processing speed in the short term in this study in elderly people with subjective, mild memory complaints. 11 p. |
| Databáze: | OpenAIRE |
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