Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties
| Autor: | Andrey S. Klymchenko, Alain Wagner, Aurélia Perino, Jean-Serge Remy, Emmanuelle Morin-Picardat, Yves Mély, D. Weltin, Patrick Neuberg, Zeinab Darwich, Nicolas Anton |
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| Přispěvatelé: | Laboratoire de Biophotonique et Pharmacologie - UMR 7213 (LBP), Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Conception et application de molécules bioactives (CAMB), Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2015 |
| Předmět: |
Cell Survival
Polymers Ultraviolet Rays [SDV]Life Sciences [q-bio] Polyethylene glycol Micelle Catalysis Cell Line Polyethylene Glycols Polymerization Surface-Active Agents chemistry.chemical_compound Drug Delivery Systems Pulmonary surfactant Oxazines Polymer chemistry Amphiphile Materials Chemistry Humans Micelles ComputingMilieux_MISCELLANEOUS Fluorescent Dyes Diacetylene Metals and Alloys Polyynes General Chemistry Fluorescence Polyacetylene Polymer Surfaces Coatings and Films Electronic Optical and Magnetic Materials Characterization (materials science) chemistry Chemical engineering Ceramics and Composites HeLa Cells |
| Zdroj: | Chemical Communications Chemical Communications, Royal Society of Chemistry, 2015, 51, pp.11595-11598 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c5cc03820k |
| Popis: | A series of polydiacetylene (PDA) - based micelles were prepared from diacetylenic surfactant bearing polyethylene glycol, by increasing UV-irradiation times. These polymeric lipid micelles were analyzed by physicochemical methods, electron microscopy and NMR analysis. Cellular delivery of fluorescent dye suggests that adjusting the polymerization state is vital to reach the full in vitro potential of PDA-based delivery systems. |
| Databáze: | OpenAIRE |
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