Neutrophil-to-lymphocyte Ratio as a Prognostic Factor for Colon Cancer in Elderly Patients: A Propensity Score Analysis
| Autor: | Akihiko Tsuchida, Junichi Mazaki, Masanobu Enomoto, Yuichi Nagakawa, Tetsuo Ishizaki, Kenji Katsumata, Hiroki Sujino, Ryutaro Udo, Kenta Kasahara, Tomoya Tago, Hiroshi Kuwabara |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Prognostic factor Neutrophils Colorectal cancer Gastroenterology Disease-Free Survival Internal medicine Overall survival Humans Medicine Lymphocyte Count Radical surgery Stage (cooking) Neutrophil to lymphocyte ratio Propensity Score Digestive System Surgical Procedures Aged Neoplasm Staging Retrospective Studies Aged 80 and over Receiver operating characteristic business.industry fungi General Medicine Prognosis medicine.disease Treatment Outcome ROC Curve Oncology Colonic Neoplasms Propensity score matching Female business |
| Zdroj: | Anticancer Research. 41:4471-4478 |
| ISSN: | 1791-7530 0250-7005 |
| DOI: | 10.21873/anticanres.15256 |
| Popis: | AIM This study aimed to evaluate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in elderly patients with Stage I-III colon cancer for long-term oncologic outcomes. PATIENTS AND METHODS We retrospectively reviewed 175 patients aged >75 years who underwent radical surgery for Stage I-III colon cancer between 2000 and 2015 at our institute. Overall survival (OS), cancer-specific survival (CSS), and relapse-free survival (RFS) were evaluated according to NLR values using propensity score analysis. Patients were allocated to the higher NLR (H-NLR) or the lower NLR (L-NLR) group with a cut-off value of 2.3, based on receiver operating characteristic curve. RESULTS Before case matching, there were significant differences between the two groups for CSS (p=0.023) and RFS (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|