Biocuration of functional annotation at the European nucleotide archive
| Autor: | Jeena Rajan, Ana Luisa Toribio, Nicole Silvester, Dimitriy Smirnov, Neil Goodgame, Petra ten Hoopen, Blaise T. F. Alako, Daniel Vaughan, Iain Cleland, Nima Pakseresht, Rasko Leinonen, Vadim Zalunin, Simon Kay, Suran Jayathilaka, Richard Gibson, Swapna Pallreddy, Ana Cerdeño-Tárraga, Clara Amid, Marc Rossello, Xin Liu, Guy Cochrane |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
European Nucleotide Archive Data curation Sequence Analysis RNA Molecular Sequence Annotation Context (language use) Sequence Analysis DNA Biology Bioinformatics World Wide Web 03 medical and health sciences 030104 developmental biology Functional annotation Genetics Database Issue General activity Biocurator Base sequence Databases Nucleic Acid Data Curation |
| Zdroj: | Nucleic Acids Research |
| ISSN: | 1362-4962 0305-1048 |
| DOI: | 10.1093/nar/gkv1311 |
| Popis: | The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data sets and major achievements. This is followed by a focus on sustainable biocuration of functional annotation, an area which has particularly felt the pressure of sequencing growth. The importance of functional annotation, how it can be submitted and the shifting role of the biocurator in the context of increasing volumes of data are all discussed. |
| Databáze: | OpenAIRE |
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