Natriuretic peptides in the evaluation of syncope in children and adolescents
| Autor: | Artur Bossowski, Wojciech Szczepański, Marcin Baran, Julianna Szczurak, Aleksandra Bogdan, Jerzy Wójtowicz |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Clinical Biochemistry Prohormone Syncope Electrocardiography Atrial natriuretic peptide Predictive Value of Tests Internal medicine Natriuretic Peptide Brain medicine Humans Tilt test Child biology business.industry Syncope (genus) Electroencephalography General Medicine biology.organism_classification Brain natriuretic peptide Peptide Fragments Cardiovascular Diseases Echocardiography Case-Control Studies Etiology Cardiology Female Differential diagnosis business Atrial Natriuretic Factor medicine.drug |
| Zdroj: | Scandinavian Journal of Clinical and Laboratory Investigation. 74:301-305 |
| ISSN: | 1502-7686 0036-5513 |
| DOI: | 10.3109/00365513.2014.883550 |
| Popis: | Natriuretic peptides have an increasing role in assessing cardiovascular conditions. The number of papers addressing their role in the evaluation of children with syncope of unclear etiology is sparse. The aim of this study was to determine whether measuring atrial natriuretic peptide (ANP) and the inactive form, N-terminal prohormone of brain natriuretic peptide (NT-proBNP) concentration in children admitted due to differential diagnosis of syncope can be helpful in establishing the most probable cause of this condition.The study included 88 patients between 9 and 18 years of age hospitalized due to syncope. The control group comprised 25 healthy children. In order to identify the cause of syncope, children with this condition were subjected to cardiologic and neurologic evaluation, and ANP and NT-proBNP concentrations were determined.The syncope group and the controls did not differ significantly in terms of natriuretic peptides concentrations. Similarly, no significant intergroup differences in natriuretic peptide concentrations were documented between children representing various types of response to the tilt test, and between the subgroups of patients with syncope of various origins.Analysis of natriuretic peptides concentrations in children with syncope does not result in unambiguous findings that would enable establishing accurate diagnosis. |
| Databáze: | OpenAIRE |
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