Presenting Symptomatology and Risk Factors in Pediatric Secondary Intracranial Hypertension due to Venous Sinus Thrombosis
| Autor: | Shalome Dsouza, Shawn C. Aylward, Brandon S. Aylward, David L. Rogers |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Nausea Pseudotumor cerebri Sinus Thrombosis Intracranial 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Developmental Neuroscience Risk Factors 030225 pediatrics Humans Medicine Cerebral venous sinus thrombosis Child Retrospective Studies Past medical history business.industry Headache medicine.disease Magnetic Resonance Imaging Thrombosis Catheter Neurology Child Preschool Pediatrics Perinatology and Child Health Vomiting Female Neurology (clinical) Intracranial Hypertension Symptom Assessment medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Pediatric Neurology. 101:53-56 |
| ISSN: | 0887-8994 |
| Popis: | Background There remains debate regarding the need for venous imaging in pediatric intracranial hypertension. Methods Records of patients aged 18 years or younger who were evaluated in the intracranial hypertension clinic at Nationwide Children's Hospital in Columbus, Ohio, were reviewed. Past medical history, diagnostic evaluation, and presenting symptoms were examined to evaluate differences in symptomatology presentation and risk factors in patients with pediatric intracranial hypertension with and without thrombosis. Results A total of 226 patients met inclusion criteria, 145 were diagnosed with primary intracranial hypertension, 81 with secondary intracranial hypertension, with 17 noted to have venous sinus thrombosis as the cause of their secondary intracranial hypertension. Of those with thrombosis, 41.2% did not have any thrombosis risk factors. Headache was the most prominent symptom, present in 73.8% (n = 107) of patients with primary intracranial hypertension, 87.5% (n = 56) of patients with secondary intracranial hypertension without thrombosis, and 82.4% (n = 14) with thrombosis. Conclusions The only clinically significant difference in presenting symptomatology between the thrombosis and the other groups was nausea or vomiting. Predisposing factors to develop thrombosis were absent in 41.2% of patients. Hence, the need for venous imaging in pediatric intracranial hypertension cannot be clearly determined by clinical presentation or risk factors alone. Patients with indwelling catheters should receive imaging in the region of their catheter to rule out catheter-associated thrombosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect