The Significant Association between Polymicrobial Diabetic Foot Infection and Its Severity and Outcomes
| Autor: | Siti Asma' Hassan, Sharifah Aisyah Syed Hitam, Nurahan Maning |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.medical_treatment 030106 microbiology polymicrobial infection 030209 endocrinology & metabolism medicine.disease_cause Group B 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus medicine microorganisms biology business.industry severity of infection Retrospective cohort study General Medicine biology.organism_classification medicine.disease Diabetic foot Proteus Amputation Staphylococcus aureus diabetes mellitus Original Article diabetic foot infection business Foot (unit) |
| Zdroj: | The Malaysian Journal of Medical Sciences : MJMS |
| ISSN: | 2180-4303 1394-195X |
| Popis: | Background Foot infection is a major complication of diabetes mellitus (DM) and its agents are usually polymicrobial. This study aims to describe the agent and determine the association between polymicrobial infections and the severity of diabetic foot infections (DFI) and their outcomes. Methods This retrospective cohort study was conducted during one year and it involved 104 patients. Their records were reviewed and assessed. The causative agents and its sensitivity pattern were noted. The results were presented as descriptive statistic and analysed. Results A total of 133 microorganisms were isolated with 1.28 microorganisms per lesion. The microorganism isolated were 62% (n = 83) GN (Gram-negative) and 38% (n = 50) GP (Gram-positive). GN microorganisms include Pseudomonas spp (28%), Proteus spp (11%), Klebsiella spp (8%) and E. coli (4%). Staphylococcus aureus (54%) was predominant among GP, followed by Group B Streptococci (26%) and Enterococcus spp (6%). Thirty patients (28.8%) had polymicrobial infections. The association between the quantity of microorganisms and severity of DFI was significant. Among severe DFI cases, 77.8% with polymicrobial microorganisms underwent amputation compared to 33.3% with monomicrobial infection. Conclusion GN microorganisms were predominantly isolated from DFIs and remained sensitive to widely used agents. Polymicrobial infections were associated with DFI severity. |
| Databáze: | OpenAIRE |
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