SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES

Autor: Antonio Auberson Martins Maciel, Kamila Rocha Maia, Everardo Albuquerque Menezes, Eduardo José Jucá Mallman, Ieda Pereira de Souza, Francisco Afrânio Cunha, Pierre Basílio Almeida Fechine, Maria da Conceição dos Santos Oliveira Cunha
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Revista do Instituto de Medicina Tropical de São Paulo
Revista do Instituto de Medicina Tropical de São Paulo, Vol 58, Iss 0
Revista do Instituto de Medicina Tropical de São Paulo, Volume: 58, Article number: 73, Published: 22 SEP 2016
ISSN: 1678-9946
0036-4665
Popis: SUMMARY Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections.
Databáze: OpenAIRE