Wound healing properties and mucilage content of Pereskia aculeata from different substrates

Autor: Lorena Blau, Cristina Pacheco Soares, Eber Goulart Carvalho, Walderez Moreira Joaquim, Renato Farina Menegon
Rok vydání: 2014
Předmět:
Zdroj: Revista Brasileira de Farmacognosia, Vol 24, Iss 6, Pp 677-682
Revista Brasileira de Farmacognosia, Vol 24, Iss 6, Pp 677-682 (2014)
Revista Brasileira de Farmacognosia, Volume: 24, Issue: 6, Pages: 677-682, Published: DEC 2014
Revista Brasileira de Farmacognosia v.24 n.6 2014
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
ISSN: 0102-695X
DOI: 10.1016/j.bjp.2014.11.008
Popis: Pereskia aculeata Mill., Cactaceae, is a cactus with high mucilage production, well-known for its nutritional properties. Folk use consists on skin injuries, and mucilage is probably involved in the wound healing activity. This work studied some aspects of its cultivation, specifically regarding soil (substrate), to correlate the effects of nutritional content to mucilage production and to the wound-healing property. Plants were grown under five different soil treatment (sand, crude soil, sand and soil, sand and cattle manure, soil and cattle manure), and after eight months extracts were prepared by turbo-extraction to obtain a crude hydroethanolic extract. We evaluated the effects of these extracts on swelling index, cytotoxicity, and in vitro wound healing property. The results show that the substrate used in cultivation may interfere with mucilage production, but not with cytotoxicity and wound healing, this shows the safety of its use, despite the soil treatment received along the various biomes where P. aculeata is cultivated. Furthermore, morphological studies demonstrated the beneficial effect of the mucilage-containing extract on the fibroblast cell culture, corroborating its folk use for wound healing. Keywords: Cactus cultivation, Cytotoxicity, Mucilage, Ora-pro-nobis, Physiologic growth parameters, Wound healing
Databáze: OpenAIRE