Wound healing properties and mucilage content of Pereskia aculeata from different substrates
Autor: | Lorena Blau, Cristina Pacheco Soares, Eber Goulart Carvalho, Walderez Moreira Joaquim, Renato Farina Menegon |
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Rok vydání: | 2014 |
Předmět: |
Ora-pro-nobis
biology Mucilage Cytotoxicity Wound healing lcsh:RS1-441 Physiologic growth parameters biology.organism_classification Cactus cultivation Manure lcsh:Pharmacy and materia medica Pharmacology Toxicology and Pharmaceutics(all) Horticulture medicine.anatomical_structure Aculeata Cactus Botany medicine Soil treatment General Pharmacology Toxicology and Pharmaceutics Pereskia aculeata Fibroblast |
Zdroj: | Revista Brasileira de Farmacognosia, Vol 24, Iss 6, Pp 677-682 Revista Brasileira de Farmacognosia, Vol 24, Iss 6, Pp 677-682 (2014) Revista Brasileira de Farmacognosia, Volume: 24, Issue: 6, Pages: 677-682, Published: DEC 2014 Revista Brasileira de Farmacognosia v.24 n.6 2014 Revista Brasileira de Farmacognosia Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
ISSN: | 0102-695X |
DOI: | 10.1016/j.bjp.2014.11.008 |
Popis: | Pereskia aculeata Mill., Cactaceae, is a cactus with high mucilage production, well-known for its nutritional properties. Folk use consists on skin injuries, and mucilage is probably involved in the wound healing activity. This work studied some aspects of its cultivation, specifically regarding soil (substrate), to correlate the effects of nutritional content to mucilage production and to the wound-healing property. Plants were grown under five different soil treatment (sand, crude soil, sand and soil, sand and cattle manure, soil and cattle manure), and after eight months extracts were prepared by turbo-extraction to obtain a crude hydroethanolic extract. We evaluated the effects of these extracts on swelling index, cytotoxicity, and in vitro wound healing property. The results show that the substrate used in cultivation may interfere with mucilage production, but not with cytotoxicity and wound healing, this shows the safety of its use, despite the soil treatment received along the various biomes where P. aculeata is cultivated. Furthermore, morphological studies demonstrated the beneficial effect of the mucilage-containing extract on the fibroblast cell culture, corroborating its folk use for wound healing. Keywords: Cactus cultivation, Cytotoxicity, Mucilage, Ora-pro-nobis, Physiologic growth parameters, Wound healing |
Databáze: | OpenAIRE |
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