Serum levels of N-terminal-pro B-type natriuretic peptide as a diagnostic marker for left ventricular dysfunction in children with end-stage renal disease on hemodialysis
| Autor: | Wegdan Mawlana, Maher Ahmed Abdel-Hafez, Mohamed Abdel-Rahman Sweylam, Amr Zoair |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class medicine.medical_treatment 030232 urology & nephrology lcsh:Medicine 030204 cardiovascular system & hematology End stage renal disease Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Renal Dialysis Internal medicine Natriuretic Peptide Brain medicine Intravascular volume status Natriuretic peptide Humans Child Dialysis Ejection fraction business.industry lcsh:R Area under the curve General Medicine Venous blood Echocardiography Doppler Peptide Fragments Endocrinology Cardiology Kidney Failure Chronic Hemodialysis business Biomarkers |
| Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 27, Iss 6, Pp 1114-1122 (2016) |
| ISSN: | 1319-2442 |
| Popis: | The objective of this study was to determine the diagnostic cutoff value of N-terminal-pro B-type natriuretic peptide (NT-pro BNP) as a marker of left ventricular (LV) dysfunction in children with end-stage renal disease (ESRD) on regular hemodialysis (HD). The study was carried out on thirty children with ESRD on regular HD and thirty healthy controls. Echocardiographic studies were done, including a conventional mode for ejection fraction, fractional shortening, tissue Doppler imaging, and longitudinal global strain by speckle tracking. Serum levels of NT-pro BNP were measured in venous blood samples before and about 30 min after HD by ELISA. Volume status was assessed by calculating interdialytic weight gain %. There were significant higher serum NT-pro BNP levels before HD (mean: 702.3 ± 274.3 ng/L) compared to controls (mean: 365.55 ± 76.5 ng/L) (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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