Meta-analysis of deep inspiration breath hold (DIBH) versus free breathing (FB) in postoperative radiotherapy for left-side breast cancer
| Autor: | Pingliang Chen, Junming Lai, Qibao Zhu, Yunhui Zhang, Fangyan Zhong, Yongbiao Luo, Rikui Zheng, Xin Long, Beiyuan Chi, Shuang Hu |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Organs at Risk medicine.medical_specialty medicine.medical_treatment Cochrane Library Anterior Descending Coronary Artery Breath Holding 03 medical and health sciences 0302 clinical medicine Breast cancer Unilateral Breast Neoplasms Medicine Humans Pharmacology (medical) Radiology Nuclear Medicine and imaging Postoperative Period Lung Radiotherapy business.industry Cancer Heart Radiotherapy Dosage General Medicine medicine.disease Coronary Vessels Confidence interval Radiation therapy 030104 developmental biology Oncology Strictly standardized mean difference 030220 oncology & carcinogenesis Meta-analysis Female Radiology business |
| Zdroj: | Breast cancer (Tokyo, Japan). 27(2) |
| ISSN: | 1880-4233 |
| Popis: | This meta-analysis evaluates the difference in deep inspiration breath hold (DIBH) versus free breathing (FB) for patients receiving postoperative radiotherapy for left breast cancer and provides a useful reference for clinical practice. The relevant controlled trials of DIBH versus FB in postoperative radiotherapy for left-side breast cancer were retrieved from the databases of PubMed, Science Direct, Cochrane Library, and Web of Science databases. The principal outcome of interest was heart dose, left anterior descending coronary artery (LADCA) dose, and left lung dose and target coverage. We calculated summary standardized mean difference (SMD) and 95% confidence intervals (CI). The meta-analysis was performed using RevMan 5.3 software. The analysis included 1019 patients from 12 observational studies, of which 576 cases were in the DIBH group and 443 cases in the FB group. Compared with the FB group, the DIBH group can have lower heart dose, left anterior descending coronary artery (LADCA) dose, and left lung dose more effectively, and the difference was statistically significant (heart dose, SMD = − 1.36, 95% CI − 1.64 ~ − 1.09, P |
| Databáze: | OpenAIRE |
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