A COMPARISON OF THE EFFECTS OF DIALYSIS AND RENAL TRANSPLANTATION ON THE SURVIVAL OF OLDER UREMIC PATIENTS
| Autor: | Karen A. Herzig, Allison M. Brown, David M. Purdie, Carmel M. Hawley, David W. Johnson, David Nicol, Russell J. Rigby |
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| Rok vydání: | 2000 |
| Předmět: |
Male
Nephrology Aging medicine.medical_specialty Patient Dropouts medicine.medical_treatment Cohort Studies Internal medicine Humans Medicine Renal replacement therapy Dialysis Kidney transplantation Aged Proportional Hazards Models Uremia Transplantation business.industry Proportional hazards model Hazard ratio Transplant Waiting List medicine.disease Kidney Transplantation Survival Analysis Surgery Renal Replacement Therapy Female business Follow-Up Studies |
| Zdroj: | Transplantation. :794-799 |
| ISSN: | 0041-1337 |
| DOI: | 10.1097/00007890-200003150-00020 |
| Popis: | Background. Patients over age 60 constitute half of all new patients accepted into the renal replacement therapy programs in Australia. However, the optimal treatment of their end-stage renal disease remains controversial. The aim of the present study was to compare survival for dialysis and renal transplantation in older patients who were rigorously screened and considered eligible for transplantation. Methods. The study cohort consisted of 174 consecutive patients over 60 who were accepted on to the Queensland cadaveric renal transplant waiting list between January 1, 1993 and December 31, 1997, Follow-up was terminated on October 1, 1998, Data were analyzed on an intention-to-transplant basis using a Cox regression model with time-varying explanatory variables. An alternative survival analysis was also performed, in which patients no longer considered suitable for transplantation were censored at the time of their removal from the waiting list. Results. There were 67 patients receiving a renal transplant, whereas the other 107 continued to undergo dialysis, These two groups were well matched at baseline with respect to age, gender, body mass index, renal disease etiology, comorbid illnesses, and dialysis duration and modality. The overall mortality rate was 0.096 per patient-year (0.131 for dialysis and 0.029 for transplant, P |
| Databáze: | OpenAIRE |
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